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Potential of Calamansi (Citrofortunella microcarpa) Fruit Peels Extract in Lowering the Blood Glucose Level of Streptozotocin Induced Albino Rats (Rattus albus)

Maria Ysabel T. Morte 1 and Liwayway H. Acero 2
1. San Beda College, Manila, Philippines
2. Department of Natural Sciences, San Beda College, Manila, Philippines
Abstract—Calamansi or calamondin is very abundant and one of the sources of staple fruit juice in the Philippines. It is grown principally for its fruit juice, since it is widely known as good source of Vitamin C. However, the peels are thrown after the extraction of the juice. The medicinal use of the peel was still unknown to many Filipinos, thus this study focuses on the potential of calamansi peels in lowering blood sugar in streptozotocin induced Albino rats. Calamansi peels were dried, macerated, and the filtrate was subjected to rotary evaporator. The extract were diluted with distilled water and administered orally in Albino rats. Twenty Albino rats served as experimental animals. They are randomly assigned in two groups. The first group, or treatment 1, (10 animals) as the control wherein they only fed with rat pellets and drinking water. The second group-treatment 2 served as the experimental animals where calamansi peel extract solution was administered orally for the entire duration of the study. Baseline blood glucose, fasting blood sugar before Stretozotocin (STZ) induction and blood sugar after three days STZ induction of both treatments showed no significant result. Final blood sugar after five days of administration of the calamansi peel extract solution showed significant result. The result revealed that calamansi peel extract solution has the potential for lowering blood glucose in Albino Rats. This implies that calamansi peel extract solution could be used as herbal medicine to lower blood glucose.
 
Index Terms—Calamansi, Calamondin, streptozotocin, blood glucose

Cite: Maria Ysabel T. Morte and Liwayway H. Acero, "Potential of Calamansi (Citrofortunella microcarpa) Fruit Peels Extract in Lowering the Blood Glucose Level of Streptozotocin Induced Albino Rats (Rattus albus)," International Journal of Food Engineering, Vol. 3, No. 1, pp. 29-34, June 2017. doi: 10.18178/ijfe.3.1.29-34
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